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Objective@#To evaluate the risk of depressive disorders using memory task indicators, so as to provide insights into clinical assessment of depressive disorders.@*Methods@#A total of 68 patients with depressive disorders undergoing treatments in the departments of psychiatrics and clinical psychology in a tertiary hospital during the period from January to September, 2021 were enrolled as the case group, while a total of 31 hospital employees, social volunteers and university students served as controls. The error rate and response time of classical memory task experiments were compared between the two groups, including implicit memory, short-term memory and working memory tasks. In addition, the predictive indicators of depressive disorders were identified using multivariable logistic regression analysis and receiver operative characteristics (ROC) curve.@*Results@#The case group included 29 men and 39 women and had a mean age of (24.12±7.40) years, including 46 subjects with an educational level higher than diploma. The control group included 15 men and 16 women and had a mean age of (26.45±6.65) years, including 23 subjects with an educational level higher than diploma. Multivariable logistic regression analysis showed significant associations of age of >18 years (OR=3.431, 95%CI: 1.259-9.350), error rate of 2-back task (OR=1.056, 95%CI: 1.016-1.097) and error rate of short-term memory tasks (OR=1.078, 95%CI: 1.009-1.152) with the development of depressive disorders. ROC curve analysis showed that the error rate of 2-back tasks showed an area under the ROC curve (AUC) of 0.730 (95%CI: 0.630-0.831), cutoff of 22.5%, sensitivity of 42.6% and specificity of 93.5% for prediction of the risk of depressive disorders, and the error rate of short-term memory tasks showed an AUC of 0.717 (95%CI: 0.605-0.829), cutoff of 23.5%, sensitivity of 67.6% and specificity of 71.0% for prediction of the risk of depressive disorders. In addition, the combination of the error rate of 2-back tasks and the error rate of short-term memory tasks showed an AUC of 0.829 (95%CI: 0.734-0.923), sensitivity of 75.0% and specificity of 80.6% for prediction of the risk of depressive disorders.@*Conclusion@#Short-term and working memory task indicators are feasible for assessment of the risk of depressive disorders.
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OBJECTIVE@#To analyze the usage of mental health assistance hotline during COVID-19 in Zhejiang province from January 25th to February 29th 2020, and summarize the characteristics of the demand for mental health services and the dynamic changes of public mental health status during COVID-19 pandemic.@*METHODS@#Both quantitative and qualitative methods were used. The calls related to pandemic were divided into four categories: medical, psychological, information and the others. The secondary categories of psychological calls were determined by text analysis. The number of calls were calculated weekly and the number of various types of calls over time were analyzed. We used stratified random sampling method to extract 600 cases of all kinds of calls related to pandemic and conducted a semantic analysis, through marking new, similar combination to form a feature set, then summed up the call content characteristics of each stage. Two hundred callers were followed up to understand how they felt about the call process in four aspects: the waiting time, call duration, the degree of problem-solving and the way to end the call.@*RESULTS@#In a total of 13 746 calls, 8978 were related to pandemic, among which 12.59%(1130/8978) were about medical issues, 26.50%(2379/8978) were about mental health, 27.18%(2440/8978) were about information regarding the pandemic and 33.74%(3029/8978) were about other pandemic related issues. Pandemic situation, relevant policy release, frequency of advertising campaigns were predictors of the number of calls per day during the pandemic (<0.05 or <0.01). The number of calls differed by gender and identities of callers (both <0.05). Finally 181 callers accepted telephone follow-up. Among them, 51.38%(93/181) of the callers thought that the waiting time was too long, 33.15%(60/181) of the callers thought that the call time was insufficient, 80.66%(146/181) of callers believed that the hotline could partially or completely resolve their concerns, and 39.23%(71/181) of the callers said the operator proposed to end the call.@*CONCLUSIONS@#s The changes of the number and content of the mental health assistance hotline calls reflected that the public mental health status experienced four stages during the pandemic: confusion, panic, boredom, and adjustment. The specialized mental health assistance hotlines should be further strengthened, and the efficiency should be improved. Mental health interventions should be tailored and adopted according to the characteristics of the public mental health status at different stages of the pandemic.
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Humans , China , Epidemiology , Coronavirus Infections , Epidemiology , Hotlines , Mental Health , Pandemics , Pneumonia, Viral , Epidemiology , Public HealthABSTRACT
Objective: To evaluate the false positive rate and false negative rate of the Chinese version of the 12-item General Health Questionnaire (GHQ-12) and the related factors in the epidemiological survey of mental ill-nesses in Zhejiang Province. Method: A total of 15000 subjects were randomly selected from the province-wide using multi-stage stratified cluster randomization. Analyses for this paper were made in the quality control sample,10% of the total 15000 subjects (1510 subjects) in which the Chinese version of Structured Clinical Interview for DSM-Ⅳ Axis Ⅰ Disorders (SCID) was used as a golden criterion, and a cutoff score of the GHQ-12 was set to ≥ 3 to define GHQ-12 cases. Results: Totally 1449 subjects (96.0%) completed both the GHQ-12 and the SCID. Adjusted for sampling effects, the false positive and negative rates of the GHQ-12 were respective 14.6% and7.8%. Adjusted for other considered correlates and sampling effects, the adjusted odds ratios (AORs) of GHQ-12 false positive with living in less economically developed urban areas (urban type Ⅱ), with self-reportedly poor physical health, with having ever sought help because of mental problems and with being currently married/co-habited were respective 2.23 (95% CI:1.24～4.01), 2.36(1.36～4.10), 1.53 (1.10～2.14) and 0.51 (0.30～0.86) while AORs of GHQ-12 false negative with being aged 35～49 year group and living in less econom-ically developed rural areas (rural type Ⅲ) were respective 2.59 (1.18～5.67) and 2.72 (1.21～6.14). Conclusion:Factors related to the GHQ-12 false positive and negative are different. The cutoff scores of the GHQ-12 should be used based on the characteristics of subjects during identifying or screening mental illnesses.
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Objective:To study the clinical therapeutic effect of acupoint stimulation on obssession.Methods:60 inpatients and outpatients of obsession were divided into two groups,a chlorimipramine group(control group)and an acupoint stimulation plus chlorimipramine group(treatment group),30 cases in each group.Their therapeutic effect and adverse effects were evaluated with Y-BOCS, HAND,BPRS and TESS,respectively.Results:The cured rate and the markedly effective rate were 26.7% and 56.6% in control group and 43.3% and 76.7% in treatment group,respectively,the treatment group being better than the control group.The adverse reactive rate was 73.33% in control group and 46.67% in the treatment group with a significant difference between the two groups(P